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. 2015 Apr 3;13:29. doi: 10.1186/s12951-015-0088-2

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© Maiolino et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Properties of DTX-PLGA/PEI and DTX-PLGA/PEI/HA NPs freeze-dried with trehalose. A) Size and zeta potential in different media. B) Release profile (37°C) of DTX from NPs dispersed in DMEM FBS+. External dialysis medium was a PBS solution at pH 7.4. Free DTX is reported as control. Results are the mean of three experiments ± SD.