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. 2015 Apr 3;13:29. doi: 10.1186/s12951-015-0088-2

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© Maiolino et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Cellular uptake of fluorescent NPs. Intracellular levels of fluorescent RHO-PLGA/PEI and RHO-PLGA/PEI/HA NPs. A549 and Calu-3 cells were incubated with 0.5 mg/ml of RHO-PLGA/PEI/HA NPs (A) and RHO-PLGA/PEI NPs (B) for 4 h and 24 h. All measurements were normalized to the fluorescence of RHO-labeled NPs in cell medium set as 100%. Results are presented as percentage (mean ± SEM) (n = 3) of the control cells.