Table 1. Baseline characteristics of all qualified studies in this meta-analysis.
| Author, year | Ancestry | Control source | Match |
Cancer |
Gender | Study design | Sample | mtDNA gene | Nuclear gene | |
|---|---|---|---|---|---|---|---|---|---|---|
| Detailed type | Classification | |||||||||
| Lan, 2008 | White | Population | Yes | Non-Hodgkin lymphoma | Lymphoma | Male | Prospective | PBL | ND1 | HGB |
| Xing, 2008 | White | Population | Yes | Renal cell carcinoma | Urogenital | Both | Retrospective | PBL | ND1 | HGB |
| Bonner, 2009 M | Asian | Population | Yes | Lung cancer | Respiratory | Male | Prospective | Sputum | ND1 | HGB |
| Bonner, 2009 F | Asian | Population | Yes | Lung cancer | Respiratory | Female | Prospective | Sputum | ND1 | HGB |
| Hosgood, 2010 | White | Population | Yes | Lung cancer | Respiratory | Male | Prospective | PBL | ND1 | HGB |
| Shen, 2010 | Mixed | Population | Yes | Breast cancer | Breast | Female | Retrospective | PBL | ND1 | HGB |
| Liao, 2011 | Asian | Population | Yes | Gastric cancer | Digestive | Female | Prospective | PBL | ND1 | HGB |
| Lynch, 2011 | White | Population | Yes | Pancreatic cancer | Digestive | Male | Prospective | PBL | ND1 | HGB |
| Qu, 2011 Overall | Asian | Population | Yes | Colorectal cancer | Digestive | Both | Retrospective | PBL | ND1 | HGB |
| Qu, 2011 M | Asian | Population | Yes | Colorectal cancer | Digestive | Male | Retrospective | PBL | ND1 | HGB |
| Qu, 2011 F | Asian | Population | Yes | Colorectal cancer | Digestive | Female | Retrospective | PBL | ND1 | HGB |
| Zhao, 2011 | Asian | Population | Yes | Hepatocellular carcinoma | Digestive | Both | Retrospective | PBL | ND1 | HGB |
| Purdue, 2012 | White | Population | Yes | Renal cell carcinoma | Urogenital | Both | Prospective | PBL | ND1 | HGB |
| Purdue, 2012 | African | Population | Yes | Renal cell carcinoma | Urogenital | Both | Prospective | PBL | ND1 | HGB |
| Thyagarajan, 2012 M | Asian | Population | NA | Colorectal cancer | Digestive | Male | Prospective | PBL | ND1 | 18s |
| Thyagarajan, 2012 F | Asian | Population | NA | Colorectal cancer | Digestive | Female | Prospective | PBL | ND1 | 18s |
| Mondal, 2013 | Asian | Hospital | Yes | Oral cancer | Head/neck cancer | Both | Retrospective | PBL | D-loop | GAPDH |
| Thyagarajan, 2013 | Asian | Population | Yes | Breast cancer | Breast | Female | Prospective | PBL | ND1 | 18s |
| Xie, 2013 M | Mixed | Population | Yes | Soft tissue sarcoma | Skeleton | Male | Retrospective | PBL | ND1 | HGB |
| Xie, 2013 F | Mixed | Population | Yes | Soft tissue sarcoma | Skeleton | Female | Retrospective | PBL | ND1 | HGB |
| Xu, 2013 M | Mixed | Population | Yes | Esophageal cancer | Digestive | Male | Retrospective | PBL | ND1 | HGB |
| Xu, 2013 F | Mixed | Population | Yes | Esophageal cancer | Digestive | Female | Retrospective | PBL | ND1 | HGB |
| Cheau-Feng, 2014 | Asian | Hospital | NA | Head/neck cancer | Head/neck cancer | Male | Retrospective | PBL | tRNAleu | 18s |
| Ghosh, 2014 | Asian | Hospital | Yes | Nasopharyngeal carcinoma | Head/neck cancer | Both | Retrospective | PBL | D-loop | GAPDH |
| Hofmann, 2014 M | Mixed | Population | Yes | Renal cell carcinoma | Urogenital | Male | Prospective | PBL | ND1 | HGB |
| Hofmann, 2014 F | Mixed | Population | Yes | Renal cell carcinoma | Urogenital | Female | Prospective | PBL | ND1 | HGB |
| Hosnijeh, 2014 | White | Population | Yes | Non-Hodgkin lymphoma | Lymphoma | Both | Prospective | PBL | ND1 | HGB |
| Huang, 2014 | Asian | Population | Yes | Colorectal cancer | Digestive | Female | Prospective | PBL | ND1 | BRCA1 |
| Jiang, 2014 | Asian | Population | Yes | Breast cancer | Breast | Female | Retrospective | PBL | ND1 | HGB |
| Kim, 2014 PLCO M | Mixed | Population | Yes | Non-Hodgkin lymphoma | Lymphoma | Male | Prospective | PBL | ND1 | HGB |
| Kim, 2014 PLCO F | Mixed | Population | Yes | Non-Hodgkin lymphoma | Lymphoma | Female | Prospective | PBL | ND1 | HGB |
| Kim, 2014 ATBC | White | Population | Yes | Non-Hodgkin lymphoma | Lymphoma | Male | Prospective | PBL | ND1 | HGB |
| Kim, 2014 PLCO-M | Mixed | Population | Yes | Lung cancer | Respiratory | Male | Prospective | PBL | ND1 | HGB |
| Kim, 2014 PLCO-F | Mixed | Population | Yes | Lung cancer | Respiratory | Female | Prospective | PBL | ND1 | HGB |
| Kim, 2014 SWHS | Asian | Population | Yes | Lung cancer | Respiratory | Female | Prospective | PBL | ND1 | HGB |
| Sun, 2014 | White | Population | Yes | Gastric cancer | Digestive | Both | Retrospective | PBL | ND1 | HGB |
| Zhang, 2014 Overall | Asian | Population | Yes | Glioma | Head/neck cancer | Both | Retrospective | PBL | ND1 | HGB |
| Zhang, 2014 M | Asian | Population | Yes | Glioma | Head/neck cancer | Male | Retrospective | PBL | ND1 | HGB |
| Zhang, 2014 F | Asian | Population | Yes | Glioma | Head/neck cancer | Female | Retrospective | PBL | ND1 | HGB |
| Zhou, 2014 | Asian | Population | Yes | Prostate cancer | Urogenital | Male | Retrospective | PBL | ND1 | HGB |
Abbreviations: M, male; F, female; PBL, peripheral blood lymphocytes.