Figure 1.

Higher anti-apoferritin antibody levels in chronic serum sickness (CSS) induced in complement factor H (CfH)^−/− mice with CfH^−/− and CD11b^−/− bone marrow. Animals were actively immunized with daily intraperitoneal doses of 4 mg of horse spleen apoferritin in saline. Five weeks later, anti-apoferritin IgG levels were measured. Data from individual mice are shown. These data from each group were normally distributed (Anderson–Darling test P>0.08). *P<0.001 versus all other groups, analysis of variance followed by Tukey's all-pairwise approach.