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Angiogenic and inflammatory parameters in melanoma B16F1 animals treated with P1G10. Tumor tissue from animals (n = 20) treated with P1G10 5 mg/kg or the control was processed and analyzed as described in Methods Section. Tumoral: (A) Hemoglobin (Hb); (B) Vascular endothelial growth factor (VEGF); (D) Tumor necrosis factor-α (TGF-α); (E) TGF-β; (F) N-acetyl-glucosaminidase (NAG) activity; Serum: (C) VEGF, * p < 0.01, Student’s t test.
