Table 1.
Types | Cell Lines | IC50 (µg/mL) |
---|---|---|
Tumoral | B16F1 | 12.7 |
4T1 | 9.1 | |
Ehrlich | 6.9 | |
Normal | CHO | 28.7 |
CIPs | 16.6 | |
BHK-21 | 19.0 |
Cells were exposed for 72 h to increasing concentrations of P1G10, and cell viability was determined by MTT metabolism. The IC50 was determined after calculating the regression of experimental data (r ≥ 0.90). Data shown are representative of three independent experiments. Tumoral cell lines: B16F1—murine nonmetastatic melanoma, 4T1 and Ehrlich—murine breast carcinomas. Normal cell lines: CHO—Chinese hamster ovary normal, CIPs—rabbit aorta endothelial cells and BHK 21—Chinese hamster kidney.