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. 2015 Apr 14;16(4):8364–8381. doi: 10.3390/ijms16048364

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© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Alignment of TLR7 amino acid sequences. Hu, Mo, Ch, Du and Pi are short for human, mouse, chicken, duck and King pigeon (Columba livia) respectively. Sequences were aligned using ClustalW and edited using Genedoc. In the pigeon sequence, the predicted signal peptide and leucine-rich repeat N-terminal (LRR-NT) and C-terminal (LRR-CT) domains are underlined. The double continuous lines denote leucine-rich repeats, and the dotted line represents the Toll/IL-1 receptor (TIR) domain. Shading was performed using the conserved mode (black shading for conserved residues and light gray shading for similar residues). The asterisk symbol stands for the number of the amino acids. GenBank accession numbers for the aligned sequences: King pigeon (Columba livia) AIK67344, duck ABK51522, chicken CAF28878, human BAG55056, and mouse AAK62676.