Table 7.
Histopathology-histomorphometry for abodminal fat pads and uterus in OVX rats.
| Groups | Control | References | RC:PCP 2:1 Mixture (g/g) | ||||
|---|---|---|---|---|---|---|---|
| Sham | OVX | RC 40 mg/kg | PCP 20 mg/kg | 30 mg/kg | 60 mg/kg | 120 mg/kg | |
| Fat pads | |||||||
| Total Th (mm) | 4.43 ± 0.92 | 9.85 ± 1.60 a | 7.70 ± 1.01 ac | 8.02 ± 0.54 ac | 7.62 ± 1.18 ac | 6.37 ± 0.57 acg | 5.55 ± 0.71 cdf |
| Adipocyte DM (μm) | 82.20 ± 12.37 | 158.17 ± 19.42 a | 117.50 ± 14.07 ac | 127.82 ± 15.14 ac | 116.00 ± 14.21 ac | 101.74 ± 11.48 cf | 99.03 ± 10.07 cf |
| Uterus | |||||||
| Total Th (mm) | 3.21 ± 0.65 | 0.54 ± 0.11 h | 0.89 ± 0.10 hj | 0.73 ± 0.09 hk | 0.84 ± 0.15 hk | 1.10 ± 0.10 hjmn | 1.45 ± 0.36 hjo |
| Epi Th (μm) | 38.47 ± 5.18 | 9.76 ± 2.26 a | 16.90 ± 1.51 ac | 19.16 ± 1.72 ac | 18.79 ± 2.93 ac | 22.81 ± 2.02 acd | 24.28 ± 2.31 acdg |
| Mucosa Th (μm) | 967.28 ± 220.32 | 176.98 ± 21.58 h | 227.65 ± 31.82 hj | 261.87 ± 32.06 hj | 286.24 ± 41.40 hj | 420.77 ± 94.19 hjo | 484.97 ± 56.84 hjln |
| UG percentage (%) | 28.78 ± 4.83 | 4.85 ± 2.17 a | 9.28 ± 1.53 ac | 11.03 ± 3.19 ac | 11.34 ± 3.50 ac | 17.67 ± 2.71 acdf | 20.10 ± 3.13 acdf |
Values are expressed mean ± S.D. of eight rats; a p < 0.01 and b p < 0.05 as compared with sham control by Tukey test; c p < 0.01 as compared with OVX control by Tukey test; d p < 0.01 and e p < 0.05 as compared with RC 40 mg/kg treated rats by Tukey test; f p < 0.01 and g p < 0.05 as compared with PCP 20 mg/kg treated rats by Tukey test; h p < 0.01 and i p < 0.05as compared with sham control by Tamhane test; j p < 0.01 and k p < 0.05 as compared with OVX control by Tamhane test; l p < 0.01 and m p < 0.05 as compared with RC 40 mg/kg treated rats by Tamhane test; n p < 0.01 and o p < 0.05 as compared with PCP 20 mg/kg treated rats by Tamhane test; OVX = Bilateral ovariectomy; PCP = Pomegranate Concentrate Powder; RC = Red clover dry extracts; Th = thickness; DM = diameter; Epi = epithelium; UG = uterine gland; FC = fatty change.