Table 4.
Associations between the three positive CNV loci and BMI z-score, WHtR.
| Locus | Type | BMI z-Score 1 | p-Value 3 | WHtR 2 | p-Value 4 |
|---|---|---|---|---|---|
| 11q11 | normal | 1.25 ± 1.55 | 0.47 ± 0.08 | ||
| deletion | 1.49 ± 1.69 | 0.063 | 0.49 ± 0.09 | 0.014 | |
| duplication | 1.29 ± 1.72 | 0.649 | 0.48 ± 0.08 | 0.258 | |
| 10q11.22 | normal | 1.26 ± 1.61 | 0.47 ± 0.08 | ||
| deletion | 1.87 ± 1.68 | 0.002 | 0.50 ± 0.08 | 0.006 | |
| duplication | 1.75 ± 2.12 | 0.069 | 0.51 ± 0.12 | 0.022 | |
| 4q25 | normal | 1.29 ± 1.64 | 0.48 ± 0.08 | ||
| deletion | 2.18 ± 1.45 | 0.007 | 0.52 ± 0.09 | 0.008 | |
| duplication | 1.31 ± 1.74 | 0.852 | 0.51 ± 0.08 | 0.187 |
1,2 BMI z-score and WHtR of each CNV state was presented as means ± SD; 3,4 p-Values were calculated by covariance analysis with adjustment for gender and age, comparing the BMI z-score and WHtR of deletion or duplication group with the copy number = 2 group; WHtR, waist to height ratio; CNV, copy number variation; BMI, body mass index.