FIG. 5.

Expression of wound healing-related factors. (A) Real-time PCR of TGF-β, CTGF, and PAI-1 in nonirradiated control skin, in irradiated-untreated skin, and in MSC- or GF-treated skin on days 28 and 50 after irradiation. Data are reported relative to control mice and normalized to GAPDH. (B) Representative immunohistochemical staining with the primary CTGF antibody. Inserts were amplified local areas from the same images. Original magnification ×20. Results are expressed as mean±SEM. P values were calculated by ANOVA with Bonferroni correction, *P<0.05; **P<0.01 compared with nonirradiated controls; ^#P<0.05; ^##P<0.01; ^###P<0.001 compared with irradiated-untreated controls.