Table 5.

The percent drug content (%) of the prepared hydrogels during storage at 2°C–8°C, 25°C, and 40°C±2°C/75%±5% RH over a period of 1 month

Formulation	Days	Drug content (%)
		2°C–8°C	25°C	40°C±2°C/75%±5% RH
TPH gel	0	99.72±2.61	99.72±2.61	99.72±2.61
	5	99.61±2.35	98.55±1.51	95.92±1.16
	10	99.34±1.94	97.68±1.01	92.16±2.18
	15	98.95±1.99	96.81±0.71	87.98±1.22
	30	98.05±2.11	95.28±1.39	80.81±0.59
FPH gel	0	99.79±2.18	99.79±2.18	99.79±2.18
	5	99.74±1.50	99.43±2.60	98.04±1.82
	10	99.69±2.59	98.74±1.59	96.19±0.55
	15	99.58±0.68	98.19±1.74	92.77±1.56
	30	99.26±1.25	97.13±1.82	85.55±1.97

Note: The values were the means ± standard deviation from three parallel measurements.

Abbreviations: TPH, transferosomal papaverine hydrochloride; FPH, free papaverine hydrochloride; RH, relative humidity.