Table 8.

Mean vital signs measurements (systolic blood pressure) before and after application of both transferosomal and free papaverine hydrochloride gel

Patient groups	Systolic blood pressure (mmHg)
	TPH gel				FPH gel
	Before application	After application	Percent decrease (%)	P-value	Before application	After application	Percent decrease (%)	P-value
Normal patient	133±5.77	107±20.8	20	Not significant	107±5.77	92±2.89	14	Not significant
Hypertensive patient	187±20.82	147±20.82	21.5	Significant	167±15.28	140±10	16	Significant
Diabetic patient	155±7.07	140±14.14	10	Not significant	133±11.55	120±10	10	Not significant

Note: The values were the means ± standard deviation from three parallel measurements.

Abbreviations: TPH, transferosomal papaverine hydrochloride; FPH, free papaverine hydrochloride.