Table 9.

Mean vital signs measurements (diastolic blood pressure) before and after application of both transferosomal and free papaverine hydrochloride gel

Patient groups	Diastolic blood pressure (mmHg)
	TPH gel				FPH gel
	Before application	After application	Percent decrease (%)	P-value	Before application	After application	Percent decrease (%)	P-value
Normal patient	77±15.28	62±10.4	19.5	Not significant	67±5.77	60±5	10	Not significant
Hypertensive patient	107±11.55	87±7.64	19	Significant	102±7.64	93±5.77	8	Significant
Diabetic patient	97±3.54	85±7.07	13	Not significant	88±7.64	83±10.41	6	Not significant

Note: The values were the means ± standard deviation from three parallel measurements.

Abbreviations: TPH, transferosomal papaverine hydrochloride; FPH, free papaverine hydrochloride.