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The number of subjects, the daily mitragynine doses to adjust for the steady state, and the loading doses in each subject
| Daily dose for 7 days (mg/day) | Loading dose (mg) in the study day (8th day) | Number of subjects |
|---|---|---|
| 6.25 | 12.5 | 3 |
| 6.25 | 6.25 | 2 |
| 9.96 | 19.92 | 1 |
| 9.96 | 9.96 | 3 |
| 11.5 | 23 | 1 |
