Table 2.
Wound closure percentage in rat skin with alkali burn during 18 days’ treatment with bFGF or BPC-157
| Cohorts (n=10) | Days
|
||||
|---|---|---|---|---|---|
| 4 | 8 | 12 | 16 | 18 | |
| Model control | 5.42±2.09 | 25.20±6.66 | 42.51±10.70 | 54.14±11.09 | 60.00±9.82 |
| bFGF (200 ng/mL) | 10.80±4.84 | 32.32±7.11 | 50.10±10.92 | 73.30±12.73** | 80.93±7.11** |
| BPC-157 (200 ng/mL) | 7.34±3.55 | 26.66±8.01 | 47.44±12.84 | 68.37±13.12** | 76.85±12.86** |
| BPC-157 (400 ng/mL) | 9.29±3.34 | 26.40±7.99 | 49.52±12.33 | 70.65±13.82** | 78.18±14.38** |
| BPC-157 (800 ng/mL) | 14.13±4.91 | 33.20±7.03 | 54.38±11.37 | 77.53±10.25** | 81.55±11.14** |
Notes: Data are presented as mean ± standard deviation and were analyzed by Student’s t-test.
**
P<0.01 versus model control.
Abbreviations: BPC-157, body protective compound 157; bFGF, basic fibroblast growth factor.