Table 3.
List of genes differentially expressed in HUVECs after BPC-157 (10 μg/mL) stimulation, determined using the Signal Transduction PathwayFinder™ RT2 Profiler™ PCR Array (>2-fold change)
| GenBank accession number | Gene name | Description | Folds up- or down regulation | P-value |
|---|---|---|---|---|
| NM_005252 | FOS | FBJ murine osteosarcoma viral oncogene homolog | 4.99 | 0.007 |
| NM_002228 | JUN | Jun proto-oncogene | 7.05 | 0.024 |
| NM_001964 | EGR-1 | Early growth response 1 | 3.70 | 0.043 |
| NM_000450 | SELE | Selectin E | 4.00 | 0.015 |
| NM_003882 | WISP1 | WNT1-inducible signaling pathway protein 1 | 2.21 | 0.008 |
| NM_130851 | BMP4 | Bone morphogenetic protein 4 | −4.53 | 0.010 |
| NM_000230 | LEP | Leptin | −5.26 | 0.021 |
| NM_001078 | VCAM1 | Vascular cell adhesion molecule 1 | −5.34 | 0.011 |
Abbreviations: BPC-157, body protective compound 157; HUVECs, human umbilical vein endothelial cells; PCR, polymerase chain reaction.