Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
miRNA sponge constructs. (a) Basic sponge with six miRNA binding sites separated by 4-nt spacers. (b) Perfect miRNA binding site on a sponge. (c) Bulged miRNA binding site on a sponge. (d) Prototype decoy consisting of a short hairpin molecule where the loop exposes a binding site for an miRNA. (e) Tough decoy (TuD) with two exposed miRNA binding sites. (f) Synthetic tough decoy (S-TuD) consisting of two fully 2′-O-methylated RNA strands exposing an miRNA binding site each
