Table 2.
SIRT1, VEGF, and Survivin expression in a lung cancer and NCT microarray
| Lung cancers (n=75)
|
NCTs (n=75)
|
P-value | |||
|---|---|---|---|---|---|
| N | % | N | % | ||
| SIRT1 | <0.001* | ||||
| 0 | 7 | 9.3 | 50 | 66.7 | |
| + | 12 | 16.0 | 20 | 26.7 | |
| ++ | 40 | 53.3 | 5 | 6.7 | |
| +++ | 16 | 21.3 | 0 | 0 | |
| VEGF | <0.001* | ||||
| 0 | 10 | 13.3 | 34 | 45.3 | |
| + | 15 | 20.0 | 27 | 36.0 | |
| ++ | 18 | 24.0 | 10 | 13.3 | |
| +++ | 32 | 42.7 | 4 | 5.3 | |
| Survivin | <0.001* | ||||
| 0 | 9 | 12.0 | 32 | 42.7 | |
| + | 17 | 22.7 | 32 | 42.7 | |
| ++ | 11 | 14.7 | 9 | 12.0 | |
| +++ | 38 | 50.7 | 2 | 2.7 | |
Note: The plus signs indicate the level of expression, and the asterisk indicates statistical significance.
Abbreviations: SIRT1, silent mating-type information regulation 2 homolog 1; VEGF, vascular endothelial growth factor; NCT, noncancerous tissue; n, sample number; N, total number.