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Kaplan-Meier survival estimates according to the status of ER (A), PR (B), age at diagnosis of brain metastasis (C), number of brain metastases (D), and subtypes of breast cancer based on the joint values of HR and HER2 status (E). The p values were determined using the log-rank test.
Abbreviations: +, positive; −, negative; CI, confidence interval; ER, estrogen receptor; HER2, human epidermal growth receptor 2; HR, hormone receptor; med, median survival; PR, progesterone receptor.
