Table 7.
West Nile virus vaccines.
| Vaccine | Vector | Dose | Immunity | Vaccination ages | Price |
|---|---|---|---|---|---|
| West-Nile Innovator® (Fort Dodge, KS, USA) |
Formalin-inactivated whole virus with MetaStim adjuvant |
Two doses at 3–6 week intervals, annual revaccination with a single dose |
Within 2 weeks after second dose |
Nonvaccinated dam: 3–4 months Vaccinated dam: 5–7 months |
US$138.30/ten doses (US$13.83/dose) |
| Recombitek (Merial Animal Health Ltd, UK) |
Lyophilized recombinant canarypox vectored West Nile virus vaccine expressing membrane and envelope proteins, plus a sterile liquid diluent |
Two im. doses at 4–6-week intervals, annual revaccination with a single dose |
Within 28 days, for 12 months |
Unknown | US$169.99/ten doses (US$16.99/dose) |
| PreveNile™ (Intervet, The Netherlands) |
Lyophilized yellow fever West Nile chimera virus vaccine expressing membrane and envelope proteins without adjuvant |
Single im. dose | Within 28 days, for 12 months |
4 months or older | US$199.99/ten doses (US$19.99/dose) |
| West-Nile Innovator® DNA (Fort Dodge) |
Plasmid encoding PrM and E gene with adjuvant (SP oil, MetaStim) |
Two doses 3 weeks apart | Within 28 days | Foals 8–9 months old were found to be protected against viremia |
US$199.99/ten doses (US$19.99/dose) |
im.: Intramuscular.