Table 10.
Very low | Low | Intermediate | High | Very high | |
---|---|---|---|---|---|
Patients, % | 21 | 38 | 18 | 14 | 8 |
Survival | |||||
All* | 9.3 | 6.3 | 3.4 | 1.2 | 0.6 |
Hazard ratio | 0.8 | 1 | 2.1 | 4.3 | 9.4 |
95% CI | 0.4-1.5 | 0.7-1.5 | 1.3-3.5 | 2.4-7.7 | 4.3-20.8 |
AML transformation | |||||
AML/25%*† | NR | NR | 2.4 | 0.8 | 0.6 |
Hazard ratio | 0 | 1 | 8.0 | 18.7 | 52.2 |
95% CI | 0-∞ | 0.3-3.9 | 3.1-20.5 | 7.0-49.7 | 13.8-198.2 |
NR indicates not reached.
Medians, years (95% CI; P < .001).
Median time to 25% AML evolution (95% CI; P < .001).