Table 3. Sensitivity assay results and patients treatment.
SN003 | LG004 | GD006 | TR008 | GA010 | PD019 | CV020 | |
---|---|---|---|---|---|---|---|
Marker | |||||||
CD133 | 55% | 60% | 70% | 60% | 65% | 55% | 70% |
CD166 | 70% | 80% | 80% | 85% | 70% | 80% | 65% |
Oct 3/4 | 70% | 75% | 75% | 70% | 80% | 75% | 80% |
ALDH1 | 90% | 90% | 80% | 80% | 70% | 90% | 80% |
CD90 | 90% | 90% | 90% | 90% | 70% | 90% | 80% |
Time to results (days) | 37 | 52 | 95 | 51 | 44 | 56 | 50 |
Tested drugs (n) | 5 | 5 | 5 | 26 | 26 | 15 | 18 |
Drugs determining mortality rate (code) | |||||||
<30% | 2,4,5,17,33 | 8,12,14,15,19 | 11,24,28,32 | 1,3,7,8,9,10,12,14,17,18,21,22,23,24,29,30,32,37,39,42,45,46 | 5,7,9,10,12,14,17,18,21,22,23,24,26,29,30,32,33,37,38,39,42,45,46 | 1,6,17,18,24,25,26,27,28,29,30,31,34,40,43 | 3,5,6,13,16,17,18,24,26,27,28,29,30,35,41,44,47 |
31–50% | 0 | 0 | 17 | 5,25,32 | 1,3,8 | 0 | 36 |
51–75% | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
76–90% | 0 | 0 | 0 | 38 | 0 | 0 | 0 |
>90% | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treatment (yes,no/drug code) | Yes/17 | No/NA | Yes/17 | No/NA | No/NA | Yes/6 | No/NA |
Response to therapy | PD | NA | SD | NA | NA | PD | NA |
Abbreviations: PD, progressive disease; NA, not applicable; SD, stable disease.
Drugs and combinations are codified as in Table 1.