Table 3b.

Clinically Relevant Leak (CRL) by health status

Characteristic	N	CRL		p value
		n	%
Hypertension				0.39
No	1897	16	0.8
Yes	2547	28	1.1
Hypertension therapy (75 missing)				0.77
No medication	263	4	1.5
Single medication	1099	11	1.0
Multiple medication	1110	13	1.2
Diabetes				0.10
No	2849	23	0.8
Yes	1595	21	1.3
Type of diabetes medication (4 missing)				0.42
No diabetes medication	232	1	0.4
Single oral medication	476	5	1.1
Multiple oral medication	369	7	1.9
Insulin (with or without oral meds)	514	8	1.6
Congestive heart failure				0.27
No	4348	42	0.9
Yes	96	2	2.1
Asthma				0.89
No	3373	33	1.0
Yes	1071	11	1.0
Inability to walk 200 ft (1 missing)				0.19
No	4359	42	1.0
Yes	84	2	2.4
History of DVT or PE				0.07
No	4271	40	0.9
Yes	173	4	2.3
Sleep apnea				0.42
No	2187	19	0.9
Yes	2257	25	1.1
CPAP				0.23
No	423	7	1.7
Yes	1834	18	1.0
Supplemental oxygen dependent (9 missing)				0.93
No	2165	24	1.1
Yes	83	1	1.2
Ischemic heart disease				0.63
No	4213	41	1.0
Yes	231	3	1.3
Pulmonary hypertension				0.47
No	4394	43	1.0
Yes	50	1	2.0
Venous edema w/ulcerations (280 missing)				0.0003
No	3961	34	0.9
Yes	203	7	3.4
Beta-blocker (61 missing)				0.45
No	3558	33	0.9
Yes	825	10	1.2
Statin/lipid-lowering agent				0.0827
No	3241	27	0.8
Yes	1203	17	1.4
Therapeutic anticoagulation				0.06
No	4227	39	0.9
Yes	217	5	2.3
Narcotic				0.22
No	3645	33	0.9
Yes	799	11	1.4
Anti-depressant (61 missing)				0.005
No	2545	16	0.6
Yes	1838	27	1.5