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. 2015 May 8;10(5):e0125771. doi: 10.1371/journal.pone.0125771

Fig 3. Lactating mammary gland.

Fig 3

Smaller panels display enlargements of the indicated areas. Size bars: 50 μm, 40x obj was used for all micrographs. A. Collagen I IHC allows visualisation of the basement membrane surrounding the dilated ducts. B. HIF-1α was not detected in the epithelial cells of the lactating gland (compare with Fig 1). C. Macrophage infiltration was sparse in the lactating mammary gland as judged by F4/80 IHC. D. A subset of cuboidal luminal epithelial cells was distinctively positive for HIF-2α. E. The percentage of HIF-2α-positive out of total luminal epithelial cells was counted in sections from three mice.