Fig 7. Expression of HIF-1α and HIF-2α during the life cycle of the mammary gland.

HIF-1α is expressed in luminal epithelial cells of pubertal and virgin adult mice. HIF-2α shows distinct expression in dispersed lactating luminal epithelial cells. HIF-2α was expressed during post-lactational involution. During involution, CK14-positive basal or progenitor cells expressed HIF-2α