Table 1.
Non-RT† | RT | Total | P | ||||
---|---|---|---|---|---|---|---|
n | % | n | % | n | % | ||
Total number of patients | 157 | 61 | 218 | ||||
Total number of reconstructed breasts | 161 | 61 | 222 | ||||
Age | <0.0001 | ||||||
Median | 51.0 | 46.5 | 50.0 | ||||
Range | 25.0 – 79.9 | 26.3 – 82.9 | 25.0 – 82.9 | ||||
BMI†† | 0.99 | ||||||
Median | 23.8 | 24.2 | 24.0 | ||||
Range | 15.6 – 43.7 | 17.7 – 40.9 | 15.6 – 43.7 | ||||
Hypertension | 50 | 32% | 8 | 13% | 58 | 27% | 0.006 |
Diabetes | 10 | 6% | 1 | 2% | 11 | 5% | 0.30 |
Smoker | 25 | 16% | 2 | 3% | 27 | 12% | 0.01 |
Bilateral Cancer | 4 | 3% | 0 | 0% | 4 | 2% | 0.59 |
Stage* | <0.0001 | ||||||
0 | 32 | 20% | 1 | 2% | 33 | 15% | |
I | 74 | 46% | 3 | 5% | 77 | 35% | |
II | 52 | 32% | 40 | 66% | 92 | 41% | |
III | 3 | 2% | 17 | 28% | 20 | 9% | |
Chemotherapy | <0.0001 | ||||||
Yes | 55 | 35% | 56 | 92% | 111 | 51% | |
No | 96 | 61% | 5 | 8% | 101 | 46% | |
Unknown | 6 | 4% | 0 | 0% | 6 | 3% | |
Hormone Therapy | 0.13 | ||||||
Yes | 104 | 66% | 48 | 79% | 152 | 70% | |
No | 50 | 32% | 13 | 21% | 63 | 29% | |
Unknown | 3 | 2% | 0 | 0% | 3 | 1% | |
Surgical Details* | |||||||
Skin Sparing Mastectomy | 34 | 21% | 22 | 35% | 56 | 25% | 0.04 |
Nipple Sparing Mastectomy | 15 | 9% | 10 | 16% | 25 | 11% | 0.16 |
SLN§ Biopsy and/or Axillary Dissection | 133 | 83% | 60 | 98% | 193 | 87% | 0.004 |
SLN Biopsy Only | 67 | 42% | 15 | 25% | 82 | 37% | |
Axillary Dissection Only | 55 | 34% | 17 | 28% | 72 | 32% | |
Alloderm/DermaMatrix Usage | 56 | 35% | 26 | 42% | 82 | 37% | 0.35 |
Permanent Implant Procedure* | 0.002 | ||||||
Saline | 87 | 54% | 24 | 39% | 111 | 50% | |
Silicone | 74 | 46% | 37 | 61% | 111 | 50% | |
Flap Performed | 0 | 0% | 4 | 6% | 4 | 2% | |
Elective Surgeries | |||||||
Contralateral Prophylactic Mastectomy | 40 | 25% | 16 | 26% | 56 | 26% | 1.00 |
Any Contralateral Procedure* | 113 | 70% | 41 | 67% | 154 | 69% | 0.51 |
Ipsilateral Nipple Reconstruction* | 76 | 47% | 23 | 37% | 99 | 45% | 0.17 |
KEY:
= Radiation Therapy,
= Body Mass Index,
= Sentinel Lymph Node,
indicates categories where denominator is total number of breasts with disease reconstructed with a tissue expander and permanent implant.