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Numbers of processed samples for single genotypes
| Genotypes | Amount of samples |
|---|---|
| S2+/+;S4+/+ | 52 |
| S2+/+;S4+/− | 107 |
| S2+/+;S4−/− | 70 |
| S2+/−;S4+/+ | 108 |
| S2+/−;S4+/− | 98 |
| S2+/−;S4−/− | 90 |
| S2−/−;S4+/+ | 43 |
| S2−/−;S4+/− | 51 |
| S2−/−;S4−/− | 10 |
| in total | 629 |
Lower number of Spry2−/−;Spry4−/− mutant embryos compared to other genotypes could be caused by their early prenatal lethality that might be related to a high incidence of additional developmental defects [48].
