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. 2015 Apr 29;12:10. doi: 10.1186/s12987-015-0005-y

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© Shah et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Pre-exposure to nicotine for 14 days reduces ischemic-reperfusion-enhanced glucose transporter (GLUT1) expression. (A) Effect of nicotine on brain microvascular GLUT1 expression in mouse brain. (B) Relative intensity of GLUT1 staining. Data represent mean ± SEM, n = 4–5, **P < 0.01 comparing the nicotine-infused group and the corresponding saline-infused sham group, ^# P < 0.05 comparing the nicotine- infused tMCAO group and saline-infused sham group using one way ANOVA analysis of the variance and Bonferonni’s multiple comparison test.