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. 2015 Mar 7;17:33. doi: 10.1186/s13058-015-0534-y

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© Min et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Breast cancer cell lines show a heterogeneous response to olaparib and SAHA. The growth inhibitory effects of olaparib and suberoylanilide hydroxamic acid (SAHA) were measured with an MTT assay. The cells were treated with increasing doses of olaparib (A) and SAHA (B) for 5 d. The percentage of surviving cells is presented in a graph with SD bars (n = 3; right). IC₅₀ values were calculated using SigmaPlot and are shown in the table (left).