Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 May 5;16:30. doi: 10.1186/s12868-015-0159-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Okada et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Schematic illustration of lentiviral vectors. Structures of the lentiviral self-inactivating expression plasmids Lv-Kir2.1, Lv-Kir-DN, Lv-GFP, Lv-synapsinP-Kir2.1, Lv-ΔCMV-synapsinP-Kir2.1, Lv-ΔCMV-LTR-RRE-cPPT-synapsinP-Kir2.1, Lv-Kv1.4, Lv-TREK, and Lv-HERG. The upstream CMV promoter was used to transcribe the viral genomic RNA. CMV, cytomegalovirus promoter; LTR, long terminal repeat; ψ, RNA packaging signal; RRE, Rev-responsive element; cPPT, central polypurine tract; β-actin, promoter of chick β-actin gene; synapsin, human synapsin I promoter; GFP, green fluorescent protein gene; NLS, nuclear localization signal; WPRE, posttranscriptional regulatory element of woodchuck hepatitis virus; ∇, deletion in the U3 region of the 3′-LTR.