. 2015 Mar 13;6(1):27. doi: 10.1186/s13287-015-0015-3

Table 2.

In vivo and Ex vivo image data

Reference		Magnetic resonance image					HistologicaI image
Reference	MF (T)	Sequence	Weighted images (TR/TE;ms)	FOV; MT; ST	Results	Date (days)	Assay	Results	Date (days)
Wen et al. [33] (2014)	1.5	FSE	T2:2000/100	40; 256×256; 1mm	H+	7,14,21,28,35,42	PB; GFAP MAP2	H+	42
Wen et al. [33] (2014)	1.5	FFE	T2*:600/18.31	40; 256×256; 1mm	H+	7,14,21,28,35,42	PB; GFAP MAP2	H+	42
Shichinohe et al. [17] (2013)	7.0	Spin echo	T2:2500/60	30×30; 512×512; 1mm	H+	2,8,14,28,49	HE; TB; GFAP NeuN	H+	N/A
Tarulli et al. [32] (2013)	3.0	FSE	T2:8/70	30×30; 512×512; 1mm	H+	7,14	PB	H+	15
Zhang et al. [16] (2013)	7.0	N/A	N/A	N/A; N/A;	H+	1,2,3,4,5,6,7	PB	H+	N/A
Liu et al. [31] (2013)	3.0	GRE	T2*:2560/6.0	6.0; N/A; 1.6 mm	H+	1, 7,21	PB; BrdU;SOX-2	H+	7,21
Lu et al. [11] (2013)	3.0	T2WI	T2*: 5000/60	200;320×320; 2mm	H+	1, 7,14, 21, 28	HE; PB	H+	28
Lu et al. [11] (2013)	3.0	DWI	T2*: 5000/60	200;320×320; 2mm	H+	1, 7,14, 21, 28	HE; PB	H+	28
Kamiya et al. [30] (2013)	7.0	3D GRE	T2*: 100/10	50×50; 256×256; 5mm	H+	1h, 1, 3, 7	BB; PKH26	H+	7
Kamiya et al. [30] (2013)	7.0	T2WI	T2*: 2000/60	50×50; 256×128; 5mm	H+	1h, 1, 3, 7	BB; PKH26	LL	7
Riegler et al. [13] (2012)	9.4	3D GRE	T2:6000/105	70×70; 512×512; 1mm	H+	24h	PB	H+	21
Riegler et al. [13] (2012)	9.4	3D GRE	T2*:6000/105	70×70; 512×512; 1mm	H+	24h	PB	H+	21
Detante et al. [29] (2012)	2.35	SE-DW	DW:2000/80	N/A; 234×234; 1mm	H+	1, 15, 28	GFAP	H+	1, 15, 28
Detante et al. [29] (2012)	2.35	SE-DW	T2*:400/25	N/A; 234×234; 1mm	H+	1, 15, 28	GFAP	Tr+	1, 15, 28
Yang et al. [28] (2011)	3.0	MPGR	T2*:596/16	292×290; 0.7mm	H+	1,15	GFAP;PB	H+	N/A
Wang et al. [15] (2011)	3.0	N/A	T2: 5840/104	45×45; 256×256; 1.5mm	H+	1, 3	GFAP;PB	H+	1, 7, 30
Wang et al. [15] (2011)	3.0	N/A	T2: 5840/104	45×45; 256×256; 1.5mm	Tr+	1, 3	GFAP;PB	Tr+	1, 7, 30
Gutiérrez-Fernandez et al. [34] (2011)	7.0	RARE	T2	N/A	H+	24h, 14	NeuN	H+	N/A
					LL		GFAP	LL
					LL		VEGF	LL
Vandeputte et al. [21] (2010)	9.4	N/A	T2: N/A	N/A	H+	24H, 2-18	MAP2	H+	N/A
Vandeputte et al. [21] (2010)	9.4	N/A	T2: N/A	N/A	H+	24H, 2-18	MAP2	Tr+	N/A
Reddy et al. [12] (2010)		Turbo Spin echo	T2: 2128/80	230×230; 700×625, 1mm,	H+	4, 16	PB	H+	16
	3.0		T2: 2548/80	80×80;94×94; 1.5mm				Tr+
	3.0		DW: 4763/50	80×80;94×94; 1.5mm				Tr+
Crabbe et al. [20] (2010)	9.4	2D MSME	T2: 6000/10; DW: 1500/27	4.0×4.0; 156×156; 0.8 mm	H+	12h, 10	MAP2	H+	N/A
Crabbe et al. [20] (2010)	9.4	2D MSME	T2: 6000/10; DW: 1500/27	N/A; N/A; 1mm	H+	12h, 10	MAP2	Tr+	N/A
Song et al. [27] (2009)		3D spin echo	T2: 3500/80	60×60; 256×160 2.0mm	N/A	N/A	N/A	N/A	N/A
		3D spin echo	T2: 3500/80	60×60; 256×160 2.0mm	N/A	N/A	PB	N/A	N/A
	1.5		T2:50/20	80× 80; 256×160; 2mm	H+	−1, 1, 3, 7,14, 21, 28	NeuN	H+	1, 28
							GFAP	Tr+
							BrdU	Tr+
Daadi et al. [26] (2009)	7.0	2D – spin echo	T2: 4000/82,5	5cm; 256×256; 0.6 mm	H+	2, 7, 14, 28, 60	hNSC	H+	60
					LL		GFP	LL
					LL		NeuN	LL
Lee et al. [19] (2009)	1.5	Turbo spin echo	T2: 2000/81	5cm; 512×512; 1.5mm	H+	−1, 1, 5, 12	hVim	H+	N/A
Lee et al. [19] (2009)	1.5	GRE	T2*: 280/20	5cm; 512×512; 1.5mm	H+	−1, 1, 5, 12	fMSC	Tr+	N/A
Walczak et al. [25] (2008)	4.7 or 9.4	3D Spin echo	T2: 1300/98	34×22×11; 128×64×3; 0.35mm	H+	−1h, 2h-1	BrdU	H+	N/A
Walczak et al. [25] (2008)	4.7 or 9.4	GRE	T2*: 300/5	10×16; 128×128	H+	−1h, 2h-1	BrdU	Tr+	N/A
Kim et al. [24] (2008)	4.7	3D Spin echo;	T1; N/A	4×3	H+	2, 7-70	hMSC	H+	Cell in core of lesion
		RARE; Flash	T2: 600/14	256×192; 1mm				Tr+
		RARE; Flash	T2*:758/30	256×192; 1mm				Tr+
Guzman et al. [23] (2008)	4.7	Spin echo	T2:2500/45	40; 256×256; 1mm	H+	−4, 3, 7,24	AP BrdU; GFAP; βTubulin	H+	N/A
Guzman et al. [23] (2008)	4.7	3D GRE	T2*:600/5	40; 256×256; 1mm	H+	−4, 3, 7,24	AP BrdU; GFAP; βTubulin	Tr+	N/A
Rice et al. [14] (2007)	7.0 or 9.4	Spin-echo multislice	T2: 1,0; N/A	3.5cm; 128×128; 1mm	H+	24h, 14	fMSC	H+	N/A
Rice et al. [14] (2007)	7.0 or 9.4	Spin-echo multislice	T2: 1,0; N/A	3.5cm; 128×128; 1mm	H+	24h, 14	GFP	Tr+	N/A
Jendelove et al. [18] (2004)	4.7	Turbo spin echo	T2:2000/42.5	3,5cm; 256×256; 0,5mm	H+	14-49	MSC*	H+	N/A
							ESC	Tr+
							GFP
Hoehn et al. [22] (2002)	7.0	2D Multislice	T2: 200/20	20×12×10 256×256×128; 0.5-0.7mm	H+	6, 8, 11, 16	ESC	H+	N/A
Hoehn et al. [22] (2002)	7.0	3D Flash	T2: 200/20	20×12×10 256×256×128; 0.5-0.7mm	H+	6, 8, 11, 16	GFP	Tr+	N/A

2D, two-dimensional; 3D, three-dimensional; AP, acidic protein; BrdU, bromodeoxyuridine; DWI, diffusion weighted imaging; ESC, (mouse) embryonic stem cell; FFE, fast field echo; fMSC, fetal mesenchymal stem cell; FOV, field of vision; FSE, fast spin echo; GE, gradient echo ; GFAP, glial fibrillary acidic protein; GFP, green fluorescence protein; GRE, gradient echo; h, hour; HE, hematoxylin and eosin; hMSC, human mesenchymal stem cell; hNSC,human embryonic stem cell-derived human neural stem cell; H+, homing (migration to target site); hVim, human vimentin antibody; LL, loss lesion; MAP2, microtubule-associated with protein 2; MF, magnetic field; MPGR, multiplanar gradient recalled acquisition in the steady state; MSC, rat bone marrow stromal cell; MSME, 2D-Multislice-multiecho ; MT, matrix; N/A, not identified; NeuN, neuronal nuclei; PB, Prussian blue; SE, diffusion-weighted; ST, thickness; RARE, rapid acquisition with relaxation enhancement; T, Tesla; T2WI, -weighted magnetic resonance imaging; T2*, star weighted imaging; TB, Trypan blue; TE, echo time; TR, repetition time; Tr+, tracking (possibility of cellular trace).