Table 2.
Coefficients, standard error of coefficients and p-values for the mixed-effects model describing the evolution of BNP over time
| Coef | Se(coef) | p-value | |
|---|---|---|---|
| (Intercept) | 2.92 | 0.95 | 0.0025 |
| Time (years) | 0.23 | 0.04 | <0.0001 |
| AVA (cm2) | −1.48 | 0.3 | <0.0001 |
| Age (years) | 0.05 | 0.007 | <0.0001 |
| Symptoms | 0.43 | 0.18 | 0.0188 |
| Male gender | −0.34 | 0.18 | 0.0607 |
| *LV ejection fraction (%) | −0.16 | 0.08 | 0.0486 |
| *Creatinine (micromol/L) | 0.4 | 0.09 | <0.0001 |
AVA = aortic valve area; LV = left ventricular. * Trasnformed LV ejection fraction and Creatinine in the models