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. 2015 Apr 11;15:24. doi: 10.1186/s12896-015-0140-1

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© Portevin et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Whole-cell MALDI-TOF MS based identification of biomarkers specific for pan-monocyte and CD16+ monocytes. A) Smoothed mass spectra quadruplicates obtained from resting pan-monocytes (n = 8, 32 red spectra) overlaid with those obtained from CD16+ monocytes (n = 7, 28 green spectra). m/z peaks significantly over-represented in pan-monocytes (left overlay plot) or CD16+ monocytes (right overlay plot) are indicated. B) Scatter-plot of quadruplicate’s averaged mass peak intensities from pan-monocytes and CD16+ monocytes from individual donor are shown for the peak at 9296.1 m/z (left) and 9720.3 m/z (right). The two-way ANOVA with Bonferroni post-tests correction was used with a significance at p < 0.001.