Table 2.
Top 20 genes ranked by real fold decrease in uterine horn from 8-week-old laboring rats (YOUNG) compared to 24-week-old laboring rats (OLDER)
| Fold decrease | Entrez gene ID | Unigene ID | Gene symbol | Entrez gene name |
|---|---|---|---|---|
| −10.0 | 24177 | Rn.9174 | Afp | Alpha-fetoprotein |
| −8.8 | 54225 | Rn.33815 | Apob | Apolipoprotein B (including Ag(x) antigen) |
| −6.9 | 287774 | Rn.1824 | Apoh | Apolipoprotein H (beta-2-glycoprotein I) |
| −5.9 | * | * | Prl | Prolactin family 2–8, subfamily, and members |
| −4.8 | 292668 | Rn.205326 | Ceacam11 | Carcinoembryonic antigen-related cell adhesion molecule 11 |
| −4.3 | 24856 | Rn.1404 | Ttr | Transthyretin |
| −4.2 | 55939 | Rn.262 | Apom | Apolipoprotein M |
| −3.9 | 315907 | Rn.214057 | Nrk | Nik-related kinase |
| −3.8 | 25105 | Rn.3835 | Nppb | Natriuretic peptide type B |
| −3.8 | 309122 | Rn.6171 | H19 | H19, imprinted maternally expressed transcript (nonprotein coding) |
| −3.7 | 691157 | Rn.182598 | Pramef12 | PRAME family member 12 |
| −3.7 | 24483 | Rn.118681 | Igf2 | Insulin-like growth factor 2 (somatomedin A) |
| −3.3 | 25065 | Rn.14799 | Slc12a1 | Solute carrier family 12 (sodium/potassium/chloride transporters), member 1 |
| −3.3 | 292697 | Rn.16843 | Apoc2 | Apolipoprotein C-II |
| −3.1 | 363493 | Rn.46187 | Taf7 l | TAF7-like RNA polymerase II, TATA-box-binding protein (TBP)-associated factor, 50 kDa |
| −3.0 | 171045 | Rn.32086 | Mmp3 | Matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| −2.9 | 171528 | Rn.21395 | Gzmb | Granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
| −2.9 | 29366 | Rn.2271 | Serpine2 | Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| −2.8 | 140914 | Rn.87449 | Olr1 | Oxidized-low-density lipoprotein (lectin-like) receptor 1 |
| −2.7 | 50669 | Rn.11206 | Prf1 | Perforin 1 (pore-forming protein) |
| −2.6 | 65029 | Rn.54493 | Aoc1 | Amiloride-binding protein 1 (amine oxidase (copper-containing)) |
All P < 0.05.
*
Represented by >1 probe on the array; and include significant fold increases in 10 genes including Prl2a1, 2c1, 4a1, 5a1, 5a2, 6a1, 7a3, 7b1, 7d1, and 8a5.