Table 4.

Main functions identified using IPA (all with P value <0.001) with differential expression in laboring uterine horn between YOUNG and OLDER rats

Top canonical pathways	Ratio
Graft-versus-Host disease signaling	5/51 (0.098)
LXR/RXR activation	7/139 (0.05)
Granulocyte adhesion and diapedesis	8/181 (0.044)
FXR/RXR activation	6/110 (0.055)
Agranulocyte adhesion and diapedesis	8/191 (0.042)

Top biological functions	Molecules
Diseases and disorders
Cancer	95
Inflammatory response	53
Neurological disease	46
Cardiovascular disease	42
Organismal injury and abnormalities	40
Molecular and cellular functions
Cellular growth and proliferation	73
Cell to cell signaling/interaction	54
Cellular movement	53
Molecular transport	52
Protein synthesis	39
Physiological system development and function
Hematological system development/function	60
Organismal development	55
Tissue morphology	47
Cardiovascular system development and function	47
Immune cell trafficking	39

IPA, ingenuity pathway analysis.