. 2015 Apr 28;3(4):e12388. doi: 10.14814/phy2.12388

Table 3.

The effect of intra-mammary LPS or saline (CTR) challenge at 7 days postpartum in Holstein cows on inflammometabolic blood biomarkers at −2, 3, 7 and 14 days from challenge.

Item	Group	Days from LPS challenge				SEM	P-value
Item	Group	−2	3	7	14	SEM	Group	Group × Time
Haptoglobin, g/L	CTR	0.78	0.73	0.39	0.40	0.13	0.94	0.01
Haptoglobin, g/L	LPS	0.68	0.79	0.47	0.38	0.13	0.94	0.01
Ceruloplasmin, µmol/L	CTR	3.17	3.28	3.24	3.39	0.23	0.02	0.75
Ceruloplasmin, µmol/L	LPS	3.36	3.62	3.69^*	3.52	0.23	0.02	0.75
Bilirubin, µmol/L	CTR	4.06	2.97	2.55	2.02	0.78	0.05	0.03
Bilirubin, µmol/L	LPS	4.20	3.66	4.16^*	2.49	0.78	0.05	0.03
ROM, mgH₂O₂/100 mL	CTR	14.3	15.2	14.7	15.4	0.9	0.14	0.37
ROM, mgH₂O₂/100 mL	LPS	14.6	16.3	16.3⁺	15.2	0.9	0.14	0.37
GOT, U/L	CTR	116.8	117.3	107.7	86.9	16.1	0.28	0.06
GOT, U/L	LPS	135.6	122.5	114.8	90.6	16.1	0.28	0.06
NEFA, μEq/L	CTR	0.460	0.321	0.320	0.288	0.060	0.02	0.39
NEFA, μEq/L	LPS	0.466	0.509	0.457	0.355	0.060	0.02	0.39
BHBA, mmol/L	CTR	0.527	0.663	0.625	0.688	0.08	0.74	0.15
BHBA, mmol/L	LPS	0.710	0.518	0.550	0.632	0.08	0.74	0.15

SEM, standard error of means; ROM, reactive oxygen metabolites; GOT, aspartate aminotransferase; NEFA, non-esterified fatty acids; BHBA, β-hydroxybutyrate.

Statistical difference between groups at the same days was established by using a conventional P value lower of 0.1 (+) or 0.05 (^*).