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. 2015 Apr 28;3(4):e12391. doi: 10.14814/phy2.12391

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© 2015 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Morphometric analysis of type IIb myofiber density in WT, mdx, mdx:utrophin^+/− (het), and dko triceps muscles. (A) The vast majority of the myofibers in the WT triceps muscles were IIb-positive. WT muscle at 6 months is shown. (B) At 6 months in the mdx:utrophin^+/− (het) muscles, groups of type IIb negative myofibers were seen indicative of fiber type grouping. Bar is 50 μm. (C) Morphometric analysis of the density of IIb myofibers showed no significant differences between any of the age-matched genotypes.