Table 1.

Serum calcium and 25-hydroxyvitamin D levels in mice fed a low (1 IU D/g) and high (10 IU D/g) vitamin D rodent chow diet. Animals placed on respective diet for 5 weeks after weaning and maintained on diet during daily saline, organic dust extract (ODE) or lipopolysaccharide (LPS) intranasal inhalation treatments for 3 weeks.

	Serum Calcium µg/mL	Serum Vitamin D ng/mL
Low Vitamin D Diet + Saline Treatment	0.83 (0.08)	6.95 (0.34)
High Vitamin D Diet+ Saline Treatment	0.99 (0.17)	83.0 (7.78)***
Low Vitamin D Diet + ODE Treatment	1.09 (0.21)	7.44 (0.41)
High Vitamin D Diet + ODE Treatment	0.83 (0.46)	74.63 (7.03)***
Low Vitamin D Diet + LPS Treatment	0.96 (0.15)	5.4 (0.27)
High Vitamin D Diet + LPS Treatment	1.0 (0.26)	62.48 (3.53)***

Mean ± SEM are shown. Asterisks (***p<0.001) denote statistical significance between respective low vs. high vitamin D treatment groups. No difference in serum calcium levels between groups. Saline is N=12 mice/group, ODE is N=8 mice/group, and LPS is N=4 mice/group combined from independent studies.