Table 1.
Clinical Characteristics of Patients in the Study.
| Clinical Characteristics | ACVE n=82 (5.3%) | NO ACVE n=1,475 (94.7%) |
|---|---|---|
|
| ||
| Median (IQR) or n (%) | ||
| Median age (yrs)† | 54.0 (43-67) | 40.0 (28-52) |
| Women | 39 (45) | 723 (49) |
| Past cardiovascular history | ||
| Hypertension* | 47 (57) | 391 (27) |
| Diabetes | 22 (27) | 247 (17) |
| Coronary disease* | 22 (27) | 88 (6) |
| Heart failure* | 15 (18) | 22 (1.5) |
| Cardiac disease† | 28 (34) | 96 (6.5) |
| Altered mental status* | 68 (83) | 917 (62) |
| ECG findings | ||
| Median heart rate | 96 (71.3-110) | 85 (74-103) |
| Median QRS | 102 (83-122) | 88 (75-100) |
| Median QTc† | 454 (428-485) | 432 (410-453) |
| Cutoff ≥ 500 ms† | 29 (35) | 152 (10) |
| Basic metabolic panel | ||
| Median bicarb (mEq/L)* | 24 (20.8-27.3) | 26 (24-29) |
| Cutoff < 20 mEq/L† | 14 (17) | 52 (3.5) |
| Number of exposures | ||
| 1 | 22 (27) | 491 (33) |
| 2 | 24 (29) | 459 (31) |
| 3 | 15 (18) | 256 (17) |
| 4+ | 15 (18) | 226 (15) |
| Unknown | 6 (7.3) | 48 (3.3) |
*
Univariate p<0.05
†
Univariate p<0.001
ACVE = adverse cardiovascular events; cardiac disease = coronary disease or heart failure; ECG = electrocardiogram; mEq/L = milliequivalents per liter; QTc = computer generated Bazett QT correction as printed on presentation ECG.