Figure 3.
Photomicrograph showing an example of ductal carcinoma in situ with negative staining by Transgelin in Figure 3A. Note the presence of myoepithelial cells positively staining for Transgelin, lending support to the in situ, noninvasive nature of the lesion. Also note several blood vessels with positive Transgelin staining in their smooth muscle walls (immunostain, magnification × 200). Figure 3B depicts an intermediate grade invasive ductal carcinoma with negative staining patterns for Transgelin and high Transgelin expression in the surrounding stroma (immunostains, magnification × 200).