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. Author manuscript; available in PMC: 2016 Jun 1.

Published in final edited form as: Am J Ophthalmol. 2015 Feb 19;159(6):1027–1035.e3. doi: 10.1016/j.ajo.2015.02.008

Galectin-3 release into tears correlates with tear film instability. Scattergrams illustrating the correlations between the levels of galectin-3 in tears (upper panel) or galectin-3 mRNA (lower panel) from the same individuals and TBUT using the Spearman rank correlation test. Significance was achieved when correlating galectin-3 in tears (R = -0.4988; P < .01), but not galectin-3 mRNA (R = -0.09697, P = 0.6304), with TBUT. Black plots, dry eye patients; white plots, normal subjects.

Galectin-3 release into tears correlates with tear film instability. Scattergrams illustrating the correlations between the levels of galectin-3 in tears (upper panel) or galectin-3 mRNA (lower panel) from the same individuals and TBUT using the Spearman rank correlation test. Significance was achieved when correlating galectin-3 in tears (R = -0.4988; P < .01), but not galectin-3 mRNA (R = -0.09697, P = 0.6304), with TBUT. Black plots, dry eye patients; white plots, normal subjects.