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Detailed model of afferent arteriole intracellular dynamics [38]. The model distinguishes the sarcoplasmic reticulum Ca2+ store from the cytosolic Ca2+, and tracks the trafficking of Ca2+ between the two compartments. MLCP, myosin light chain phosphatase; CaM, calmodulin; PMCA, plasma membrane Ca2+ pump; NCX, Na+/Ca2+ exchanger, SERCA, sarco/endoplasmic Ca2+ pump; RyR, ryanodine receptor; IP3R, inositol triphosphate receptor. Figure adopted from Ref. [38].
