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A erent arteriole myogenic mechanism. Membrane depolarization leads to opening of Ca2+ channels and increase of cytosolic [Ca2+]. Increased [Ca2+] leads to crossbridge phosphorylation, increased muscle tone, and vasoconstriction. Membrane polarization, having the opposite effects, leads to vasodilation. The myogenic response (red arrows) senses blood pressure and adjusts membrane potential accordingly through the activity of non-selective cation channels.
