. Author manuscript; available in PMC: 2016 Jan 16.

Published in final edited form as: Hepatol Res. 2014 Dec 9;45(11):1110–1123. doi: 10.1111/hepr.12449

Table 1.

Clinicopathological characterization of the liver tissues analyzed by BS–PCR DNA sequencing

Characteristic	Normal (n = 3)	Hepatitis (n = 5)	Cirrhosis (n = 5)	HCC and adjacent non-HCC (n = 5)
Mean age (years) ± SD	35.67 ± 19.14^†	60.6 ± 14.9	60 ± 10.4	63 ± 10.7
Male/female (n)	3/0	1/4	3/2	4/1
HBV/HCV/both/non-viral or unknown (n)	–	1/2/1/1	2/2/0/1	1/2/0/2
Stage 1/2/3/4/unknown (n)	–	–	–	3/2/0/0/0
Grade 1/2/3/unknown (n)	–	–	–	0/2/3/0
Mean size of tumor (cm) ± SD	–	–	–	7.1 ± 2.2
AFP levels ≤20/>20 ng/mL/unknown (n)	–	–	–	1/4/0

^†

The individual age for the three normal liver subjects is 57, 20 and 30 years.

AFP, α-fetoprotein; BS–PCR, bisulfite polymerase chain reaction; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; HCV, hepatitis C virus; SD, standard deviation.