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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Curr Opin Immunol. 2014 Jul 31;30:63–71. doi: 10.1016/j.coi.2014.07.001

Figure 3. Association with isoform specific gene expression for OAS1, a key IFN inducible gene involved in anti-viral defence.

Figure 3

In human monocytes exposed to IFNγ, a highly significant cis eQTL shows directional association by allele dependent on the interrogating Illumina expression probe [9••]. The associated SNP, rs10774671 is reported to modulate alternative splicing [42] and to be a risk allele for West Nile virus [43], antibody levels to measles mumps and rubella vaccination [44] and Dengue outcomes [45].