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Uptake of [3H]-digoxin in the presence of inhibitors (GF120918 and ketoconazole) and RX-10045 in MDCKII-MDR1 cells. [3H]-digoxin served as control. Data are shown as mean±SEM (n=4). *P<0.05 versus control (paired t-test). MDCK, Madin-Darby canine kidney; MDR, multidrug resistance; SEM, standard error of mean.
