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The perforation margin in the chronic suppurative otitis media (CSOM) model. Figure demonstrates the perforation edge showing a mucosal layer migrated laterally to be directly adjacent to the keratinocyte layer (arrow) with a thickened fibrous layer containing inflammatory cells. These findings are commonly observed in human chronic TM perforations. Scale bar=10 μm (magnification 40×). Color images available online at www.liebertpub.com/tea
