Table 2.
Primary Drug-Resistant Mutations Associated with Protease and Reverse Transcriptase Genes Among Treatment Naïve Participants
| Targeting drugs of resistant mutations | Resistant profile | ||||||
|---|---|---|---|---|---|---|---|
| Sample | Subtype | PI | NRTI | NNRTI | Low | Intermediate | High |
| 916 | CRF07_BC | M46L | NFV | ||||
| 964 | CRF07_BC | T215I | AZT, d4T | ||||
| 1128 | CRF07_BC | K103N | EFV, NVP | ||||
| 1141 | CRF07_BC | D67N | AZT, d4T | ||||
| 1415 | CRF07_BC | G190A | EFV | NVP | |||
PI, protease inhibitors; NRTI, nucleoside reverse transcriptase inhibitors; NNRTI, nonnucleoside reverse transcriptase inhibitors; AZT, zidovudine; d4T, stavudine; EFV, efavirenz; NFV, nelfinavir; NVP, nevirapine.