Table 1. Seven nonessential A. nidulans phosphatases null mutants.
A. nidulans Genes | Familya | Subfamilyb | Class/Domainc | S. Cerevisiae Gene | E Value | Identity (%) |
---|---|---|---|---|---|---|
AN4544 (msgA) | PTP | Dual-specificity | DSP | MSG5 | 1e-22 | 30 |
AN0129 (ppsA) | PTP | Dual-specificity | DSP | PPS1 | 1e-51 | 31 |
AN10077 (psrA) | S/T | Asp-based | HAD | PSR1 | 3e-92 | 69 |
AN0914 (ptcD) | S/T | PPM | PP2C | PTC6 | 1e-25 | 33 |
AN5722 (ptcE) | S/T | PPM | PP2C | PTC5 | 5e-112 | 44 |
AN4896 (ptpB) | PTP | Classical | PTP | PTP1 | 3e-39 | 33 |
AN10138 (sdpA) | PTP | Dual-specificity | DSP | SDP1 | 9e-05 | 33 |
Seven nonessential A. nidulans phosphatases null mutants that cannot germinate on glucose as a sole carbon source and the homologous functionally characterized S. cerevisiae phosphatases.
Family abbreviations: S/T, serine/threonine; PTP, protein tyrosine phosphatase.
Subfamily abbreviations: Asp-based, aspartate-based phosphatase.
Class/domain abbreviations: PP2Cc, protein phosphatase 2C catalytic subunit; PPM, Mg2+ or Mn2+-dependent protein phosphatase; HAD, haloacid dehalogenase; PTP, protein tyrosine phosphatase catalytic subunit; DSPc, dual-specificity phosphatase catalytic subunit.