Fig. 1.

Loss of the novel UDP-galactose transporter, Senju, causes abnormalities in immune organs. (A–C) Spontaneous melanization in the hemocoel and lymph glands in third-instar larvae of senju¹. senju¹ (B) and WT (C) lymph glands at high magnification. (Scale bars, 250 μm.) (D–I) Lymph glands from WT (D, F, and H) and senju¹ (E, G, and I) late third-instar larvae carrying the Dome-MESO transgene (16) were stained with antibodies against the plasmatocyte marker, Nimrod (D and E); the undifferentiated cell marker, Dome-lacZ (F and G); and the lamellocyte marker, L1 (H and I) (green). Nuclei are stained with DAPI (blue). D′–I′ show merged images. (Scale bars, 200 μm.) The white dashed lines outline the lymph glands.